Complement C3

A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.

Also Known As:

C3 Complement; Complement 3; Complement Component 3; C3 Precursor; Complement C3 Precursor; Precursor-Complement 3; Pro-C3; Pro-Complement 3; C3 Precursor, Complement; C3, Complement; Complement, C3; Component 3, Complement; Precursor Complement 3; Precursor, C3; Precursor, Complement C3; Pro C3; Pro Complement 3

Pharmalogical Action Categories:

Immunologic Factors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Blood Proteins: 12459
    - Acute-Phase Proteins: 5159
      - Complement C3: 1636
    - Immunoproteins: 43
      - Complement System Proteins: 33379
        Complement C3: 1636

Runqi Fu Selected Research

Runqi Fu Research Topics

Disease

Drug/Important Bio-Agent (IBA)